The physiological shape of endothelial cells greatly varies among different types of blood vessels. Not all types of endothelial cells are elongated in their physiological environment.
HUVEC, for example, elongate in the first period of flow. In order to cover the whole surface, the cells increase their surface by elongating in the flow direction. After this flow period, the cell layer grows to an oriented cobblestone pattern, which no longer shows significant elongation.
Please find more details in our scientific poster.

Still can’t find the answer?

Contact customer support and we will reply as soon as possible.