Why are my cells not elongated under flow conditions?
The physiological shape of endothelial cells greatly
varies among different types of blood vessels. Not all types of endothelial
cells are elongated in their physiological environment.
HUVEC, for example, elongate in the first period of flow. In order to cover the
whole surface, the cells increase their surface by elongating in the flow direction.
After this flow period, the cell layer grows to an oriented cobblestone
pattern, which no longer shows significant elongation.
Please find more details in our scientific
poster.
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